The assignment of absolute configuration of cyanohydrins by NMR.
نویسندگان
چکیده
Derivatization of aldehyde cyanohydrins as (R)- and (S)-MPA esters and comparison of the corresponding 1H- and 13C-NMR spectra allows the assignment of their absolute configuration.
منابع مشابه
13C NMR as a general tool for the assignment of absolute configuration.
(13)C NMR, alone or in combination with (1)H NMR, allows the assignment of the absolute configuration of chiral alcohols, amines, carboxylic acids, thiols, cyanohydrins, sec,sec-diols and sec,sec-aminoalcohols, derivatized with appropriate chiral auxiliaries. This extends the assignment possibilities of NMR to fully deuterated and to nonproton containing compounds.
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عنوان ژورنال:
- Chemical communications
دوره 13 شماره
صفحات -
تاریخ انتشار 2006